The microbiome refers to the collective genomes of all the microorganisms that live in and on the human body, including bacteria, viruses, fungi, and other microbes. These microbes play a vital role in maintaining human health, as they help to regulate the immune system, metabolize nutrients, and protect against pathogens.
The microbiome is unique to each individual and can be influenced by many factors, including diet, genetics, and environmental exposure. Research has shown that imbalances in the microbiome, also known as dysbiosis, can contribute to the development of various health conditions, such as obesity, inflammatory bowel disease, and certain types of cancer.
In recent years, the study of the microbiome has become an important area of research, and scientists are working to better understand the role that these microbes play in human health and disease. For example, probiotics, which are live microorganisms that are similar to the beneficial bacteria found in the human gut, have been shown to have a positive impact on the microbiome and have been used to treat a variety of health conditions, including irritable bowel syndrome and antibiotic-associated diarrhea.
Comprehensive Microbiome Assessment and Stool Analysis
- Complete Microbiome Analysis
- Result specific commentary provided
- True multiple specimen parasitology analysis
- Expanded susceptibilities testing
- Superb turnaround time
- Value priced
Gastrointestinal (GI) complaints are among the most common reasons that patients seek medical care. Symptoms associated with GI disorders include persistent diarrhea, constipation, bloating, indigestion, irritable bowel syndrome and malabsorption.
Comprehensive stool analysis is an invaluable non-invasive diagnostic assessment that permits practitioners to objectively evaluate the status of beneficial and imbalanced commensal bacteria including clostridium species, pathogenic bacteria, yeast/fungus and parasites. Precise identification of pathogenic species and susceptibility testing greatly facilitates selection of the most appropriate pharmaceutical or natural treatment agent(s).
Important information regarding the efficiency of digestion and absorption can be gleaned from the measurement of the fecal levels of elastase (pancreatic exocrine sufficiency), muscle and vegetable fibers, carbohydrates, and steatocrit (% total fat).
Inflammation can significantly increase intestinal permeability and compromise assimilation of nutrients. The extent of inflammation, whether caused by pathogens or inflammatory bowel disease (IBD), can be assessed and monitored by examination of the levels of biomarkers such as lysozyme, lactoferrin, white blood cells and mucus. These markers can be used to differentiate between inflammation associated with potentially life threatening inflammatory bowel disease (IBD), which requires life long treatment, and less severe inflammation that can be associated with the presence of enteroinvasive pathogens. Lactoferrin is only markedly elevated prior to and during the active phases of IBD, but not with IBS. Monitoring fecal lactoferrin levels in patients with IBD can therefore facilitate timely treatment of IBD, and the test can be ordered separately. Since the vast majority of secretory IgA (sIgA) is normally present in the GI tract where it prevents binding of pathogens and antigens to the mucosal membrane, it is essential to know the status of sIgA in the gut. sIgA is the only bona fide marker of humoral immune status in the GI tract.
Cornerstones of good health include proper digestion of food, assimilation of nutrients, exclusion of pathogens and timely elimination of waste. To obtain benefits from food that is consumed, nutrients must be appropriately digested and then efficiently absorbed into portal circulation. Microbes, larger sized particles of fiber, and undigested foodstuffs should remain within the intestinal lumen. Poor digestion and malabsorption of vital nutrients can contribute to degenerative diseases, compromised immune status, and nutritional deficiencies. Impairment of the highly specific nutrient uptake processes, or compromised GI barrier function (as in “leaky gut syndrome”) can result from a number of causes including: low gastric acid production, chronic maldigestion, food allergen impact on bowel absorptive surfaces, bacterial overgrowth or imbalances (dysbiosis); pathogenic bacteria, yeast or parasites and related toxic irritants, and the use of NSAID’s and antibiotics. Impairment of intestinal functions can contribute to the development of food allergies, systemic illnesses, autoimmune disease, and toxic overload from substances that are usually kept in the confines of the bowel for elimination. Efficient remediation of GI dysfunctions incorporates a comprehensive guided approach that should include consideration of elimination of pathogens and exposure to irritants, supplementation of hydrochloric acid, pancreatic enzymes and pre- and probiotics, and repair of the mucosal barrier.